KF21213

KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors. KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM) .

Product Specifications

CAS Number

155271-17-3

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/KF21213.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C)N(C)C2=C(N(C)C(/C=C/C3=CC=C(OC)C(C)=C3C)=N2)C1=O

Molecular Formula

C19H22N4O3

Molecular Weight

354.40

References & Citations

[1]Wang WF, et al. Carbon-11-labeled KF21213: a highly selective ligand for mapping CNS adenosine A (2A) receptors with positron emission tomography. Nucl Med Biol. 2000 Aug;27 (6) :541-6.