Flosulide
Flosulide is a potent and selective COX-2 inhibitor, used for the treatment for inflammatory diseases.
Product Specifications
CAS Number
80937-31-1
Product Name Alternative
ZK 38997; CGP 28238
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Flosulide.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=CC2=C(C(CC2)=O)C=C1OC3=CC=C(F)C=C3F)=O
Molecular Formula
C16H13F2NO4S
Molecular Weight
353.34
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Turull A, et al. Acute effects of the anti-inflammatory cyclooxygenase-2 selective inhibitor, flosulide, on renal plasma flow and glomerular filtration rate in rats. Inflammation. 2001 Apr;25 (2) :119-28.|[2]Zimmermann KC, et al. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res. 1999 Jan 1;59 (1) :198-204.|[3]Heise G, et al. Different actions of the cyclooxygenase 2 selective inhibitor flosulide in rats with passive Heymann nephritis. Nephron. 1998 Oct;80 (2) :220-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
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