Tritoqualine
Tritoqualine is a histidine decarboxylase inhibitor, that inhibits the release of histidine[1][2].
Product Specifications
CAS Number
14504-73-5
Product Name Alternative
Inhibostamin; Hypostamine
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Amino Acid Decarboxylase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Tritoqualine.html
Solubility
10 mM in DMSO
Smiles
O=C1OC(C2N(C)CCC3=C2C(OC)=C(OCO4)C4=C3)C5=C1C(N)=C(OCC)C(OCC)=C5OCC
Molecular Formula
C26H32N2O8
Molecular Weight
500.54
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Ishii K, et al. Therapeutic effect of histidine decarboxylase inhibitor on chronic active hepatitis. Gastroenterol Jpn. 1978;13 (2) :105-10.|[2]Yuasa S, et al. Suppressive effect of tritoqualine on lipid peroxidation and enzyme leakage induced by carbon tetrachloride in rat hepatocytes. Jpn J Pharmacol. 1986 Jun;41 (2) :205-10.|[3]Umezu K, et al. Inhibitory effect of tritoqualine (TRQ) on histamine release from mast cells. Jpn J Pharmacol. 1985 Jun;38 (2) :153-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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