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Tritoqualine

Tritoqualine is a histidine decarboxylase inhibitor, that inhibits the release of histidine[1][2].

Product Specifications

CAS Number

14504-73-5

Product Name Alternative

Inhibostamin; Hypostamine

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Amino Acid Decarboxylase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Tritoqualine.html

Solubility

10 mM in DMSO

Smiles

O=C1OC(C2N(C)CCC3=C2C(OC)=C(OCO4)C4=C3)C5=C1C(N)=C(OCC)C(OCC)=C5OCC

Molecular Formula

C26H32N2O8

Molecular Weight

500.54

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Ishii K, et al. Therapeutic effect of histidine decarboxylase inhibitor on chronic active hepatitis. Gastroenterol Jpn. 1978;13 (2) :105-10.|[2]Yuasa S, et al. Suppressive effect of tritoqualine on lipid peroxidation and enzyme leakage induced by carbon tetrachloride in rat hepatocytes. Jpn J Pharmacol. 1986 Jun;41 (2) :205-10.|[3]Umezu K, et al. Inhibitory effect of tritoqualine (TRQ) on histamine release from mast cells. Jpn J Pharmacol. 1985 Jun;38 (2) :153-60.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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