What is the catalog number for HS-173?

The catalog number for HS-173 is HY-15868.

What sizes are available for HS-173?

HS-173 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does HS-173 come in?

HS-173 is available in 6 different pack sizes.

HS-173 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HS-173?

HS-173 is manufactured by QuantiMol.

What is the estimated delivery time for HS-173?

Estimated delivery time for HS-173 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HS-173?

The safety data sheet for HS-173 is available here: http://file.medchemexpress.com/batch_PDF/HY-15868/HS-173-SDS-MedChemExpress.pdf.

HS-173

HS-173 is a novel PI3K inhibitor, that is used for cancer treatment.

Product Specifications

CAS Number

1276110-06-5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; PI3K

Type

Reference compound

Related Pathways

Apoptosis; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/HS-173.html

Purity

99.04

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CN=C2C=CC(C3=CC(NS(=O)(C4=CC=CC=C4)=O)=CN=C3)=CN21)OCC

Molecular Formula

C21H18N4O4S

Molecular Weight

422.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Rumman M, et al. HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer. Oncotarget. 2016 Oct 25|[2]Son MK, et al. HS-173, a novel PI3K inhibitor, attenuates the activation of hepatic stellate cells in liver fibrosis. Sci Rep. 2013 Dec 11;3:3470|[3]Yun SM, et al. Synergistic anticancer activity of HS-173, a novel PI3K inhibitor in combination with Sorafenib against pancreatic cancer cells. Cancer Lett. 2013 May 1;331 (2) :250-61|[4]Kim O, et al. Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesis. J Med Chem. 2011 Apr 14;54 (7) :2455-66.