What is the catalog number for AVE-8134?

The catalog number for AVE-8134 is HY-U00014.

What sizes are available for AVE-8134?

AVE-8134 is available in the following size(s): 1 Each.

Is AVE-8134 in stock?

AVE-8134 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AVE-8134?

AVE-8134 is manufactured by QuantiMol.

What is the estimated delivery time for AVE-8134?

Estimated delivery time for AVE-8134 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AVE-8134?

The safety data sheet for AVE-8134 is available here: http://file.medchemexpress.com/batch_PDF/HY-U00014/.

AVE-8134

AVE-8134 is a potent PPARα agonist, with EC50 values of 100 and 3000 nM for human and rodent PPARα receptor, respectively.

Product Specifications

CAS Number

304025-09-0

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/AVE-8134.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=C(COCCCOCC2=COC(C3=CC=CC=C3)=N2)C=CC=C1C

Molecular Formula

C22H23NO5

Molecular Weight

381.42

References & Citations

[1]Schafer HL, et al. AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats. Acta Pharmacol Sin. 2012 Jan;33 (1) :82-90.|[2]Linz W, et al. The peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist, AVE8134, attenuates the progression of heart failure and increases survival in rats. Acta Pharmacol Sin. 2009 Jul;30 (7) :935-46.