Temarotene

Temarotene is an orally administered, particular arotinoid[1].

Product Specifications

CAS Number

[75078-91-0]

Product Name Alternative

Ro 15-0778

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Temarotene.html

Solubility

10 mM in DMSO

Smiles

C/C(C1=CC2=C(C(C)(C)CCC2(C)C)C=C1)=C\C3=CC=CC=C3

Molecular Formula

C23H28

Molecular Weight

304.47

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Olsen DR, et al. Suppression of ornithine decarboxylase gene expression by retinoids in cultured human keratinocytes. J Invest Dermatol. 1990 Jan;94 (1) :33-6.|[2]Fenina N, et al. Concentration of Temarotene (Ro 15-0778) and its metabolite Ro 14-6113 in plasma and skin of hairless rat. Skin Pharmacol. 1993;6 (1) :61-4.