Scyliorhinin II
Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.
Product Specifications
CAS Number
112748-19-3
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Scyliorhinin_II.html
Solubility
10 mM in H2O
Smiles
O=C1N2[C@@](C(N[C@H](C(NCC(N3[C@](CCC3)([H])C(N[C@H](C(N[C@@H](CSSC[C@@H]1NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H]4N(CCC4)C([C@@H](N)CO)=O)=O)=O)=O)=O)=O)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)CC(O)=O)=O)=O)=O)CC(O)=O)=O)([H])CCC2
Molecular Formula
C77H119N21O26S3
Molecular Weight
1851.09
References & Citations
[1]Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144 (1) :109-11.|[2]Raffa RB, et al. Scyliorhinin-I and -II induce reciprocal hindlimb scratching in mice: differentiation of spinal and supraspinal neurokinin receptors in vivo. Neurosci Lett. 1993 Aug 6;158 (1) :87-91.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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