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Scyliorhinin II

Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.

Product Specifications

CAS Number

112748-19-3

UNSPSC

12352209

Target

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Scyliorhinin_II.html

Solubility

10 mM in H2O

Smiles

O=C1N2[C@@](C(N[C@H](C(NCC(N3[C@](CCC3)([H])C(N[C@H](C(N[C@@H](CSSC[C@@H]1NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H]4N(CCC4)C([C@@H](N)CO)=O)=O)=O)=O)=O)=O)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)CC(O)=O)=O)=O)=O)CC(O)=O)=O)([H])CCC2

Molecular Formula

C77H119N21O26S3

Molecular Weight

1851.09

References & Citations

[1]Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144 (1) :109-11.|[2]Raffa RB, et al. Scyliorhinin-I and -II induce reciprocal hindlimb scratching in mice: differentiation of spinal and supraspinal neurokinin receptors in vivo. Neurosci Lett. 1993 Aug 6;158 (1) :87-91.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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