Prolactin Releasing Peptide (12-31), human

Prolactin Releasing Peptide (12-31), human is a fragment of the prolactin releasing peptide (PrRP) . Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin.

Product Specifications

CAS Number

[235433-36-0]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Prolactin_Releasing_Peptide__12-31_,_human.html

Purity

98.85

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@@H](NC([C@H](C)NC([C@H]4N(CCC4)C([C@H](CC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H]5N(CCC5)C([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O

Molecular Formula

C104H158N32O26

Molecular Weight

2272.57

References & Citations

[1]Roland BL, et al. Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery. Endocrinology. 1999 Dec;140 (12) :5736-45.|[2]Langmead CJ, et al. Characterization of the binding of [ (125) I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Br J Pharmacol. 2000 Oct;131 (4) :683-8.|[3]Seal LJ, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141 (5) :1909-12.