Substance P, Free Acid

Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P.

Product Specifications

CAS Number

[71977-09-8]

UNSPSC

12352209

Target

Endogenous Metabolite; Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Substance_P,_Free_Acid.html

Solubility

10 mM in H2O

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Molecular Formula

C63H97N17O14S

Molecular Weight

1348.61

References & Citations

[1]Patel AB, et al. Substance P (free acid) adopts different conformation than native peptide in DMSO, water and DPPC bilayers. J Biomol Struct Dyn. 2001 Aug;19 (1) :129-38.