Substance P (1-7)
Substance P (1-7) is a fragment of the neuropeptide, substance P (SP) . Substance P (1-7) gives depressor and bradycardic effects when applied to the nucleus tractus solitarius[1].
Product Specifications
CAS Number
68060-49-1
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Substance_P_1-7.html
Solubility
10 mM in H2O
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C41H65N13O10
Molecular Weight
900.04
References & Citations
[1]Herrera-Marschitz M, et al. The substance P (1-7) fragment is a potent modulator of substance P actions in the brain. Brain Res. 1990 Jun 25;521 (1-2) :316-20.|[2]Sakurada T, et al. Substance P (1-7) antagonizes substance P-induced aversive behaviour in mice. Neurosci Lett. 1988 Dec 19;95 (1-3) :281-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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