Tanshinone IIA (Standard)
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
Product Specifications
CAS Number
568-72-9
Product Name Alternative
Dan Shen ketone (Standard)
UNSPSC
12352005
Target
Reference Standards; VEGFR
Type
Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/tanshinone-iia-standard.html
Smiles
O=C(C1=C2C=CC3=C1CCCC3(C)C)C(C4=C2OC=C4C)=O
Molecular Formula
C19H18O3
Molecular Weight
294.34
References & Citations
[1]Xie J, et al. The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line. Acta Pharm Sin B. 2015 Nov;5 (6) :554-63.|[2]Zhang Z, et al. Tanshinone IIA inhibits apoptosis in the myocardium by inducing microRNA-152-3p expression and thereby downregulating PTEN. Am J Transl Res. 2016 Jul 15;8 (7) :3124-32.|[3]Su CC, et al. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo. Oncol Rep. 2016 Aug;36 (2) :1173-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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