SVC-02
Product Specifications
CAS Number
2911548-33-7
UNSPSC Description
SVC-02 is a vasohibin (VASH) inhibitor with an IC50 value of 11 nM. SVC-02 reduces tubulin detyrosination. SVC-02 has the potential for the research of reduce myo-cardial stiffness and improve relaxation in Heart failure with preserved ejection fraction (HFpEF)[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/svc-02.html
Smiles
CCOC1=CC=C(C[C@H](NC([C@H]2O[C@@H]2C(N[C@@H](CC3=CC=C(OCC)C=C3)C(OCC)=O)=O)=O)C(OCC)=O)C=C1
Molecular Weight
570.63
References & Citations
[1]Eaton DM, et al. Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction. Sci Transl Med. 2024 Jul 17;16(756):eadm8842.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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