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SVC-02

Product Specifications

CAS Number

2911548-33-7

UNSPSC Description

SVC-02 is a vasohibin (VASH) inhibitor with an IC50 value of 11 nM. SVC-02 reduces tubulin detyrosination. SVC-02 has the potential for the research of reduce myo-cardial stiffness and improve relaxation in Heart failure with preserved ejection fraction (HFpEF)[1].

Target Antigen

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/svc-02.html

Smiles

CCOC1=CC=C(C[C@H](NC([C@H]2O[C@@H]2C(N[C@@H](CC3=CC=C(OCC)C=C3)C(OCC)=O)=O)=O)C(OCC)=O)C=C1

Molecular Weight

570.63

References & Citations

[1]Eaton DM, et al. Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction. Sci Transl Med. 2024 Jul 17;16(756):eadm8842.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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