Cyclosporin A-Derivative 1
Cyclosporin A-Derivative 1 is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
Product Specifications
CAS Number
1487360-85-9
UNSPSC
12352209
Target
Calcineurin; Cyclophilin
Type
Peptides
Related Pathways
Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Cyclosporin_A-Derivative_1.html
Solubility
H2O
Smiles
[F-][B+3]([F-])([F-])[F-].O=C([C@@](C(C)C)([H])N(C)C([C@H](CC(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N(C)C([C@@](C(C)C)([H])NC([C@H](CC(C)C)NC)=O)=O)=O)=O)=O)=O)=O)N(C)[C@]([C@H](OC(C)=O)[C@H](C)C/C=C/C)([H])C(N[C@@H](CC)C(N(C)CC(OC)=O)=O)=O.[H+]
Molecular Formula
C65H118BF4N11O14
Molecular Weight
1364.50
References & Citations
[1]Fabrice Gallou, et al. Process for the manufacture of cyclic undecapeptides. WO 2013167703 A1.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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