Neuromedin U, rat

Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.

Product Specifications

CAS Number

[117505-80-3]

Product Name Alternative

Neuromedin U (rat) ; Rat neuromedin U-23

UNSPSC

12352209

Target

Neuromedin U Receptor (NMUR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Neuromedin_U,_rat.html

Solubility

H2O

Smiles

C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=CC=C3)NC(CNC(CNC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC([C@@H](NC(=O)[C@H]5N(C(CNC([C@@H](NC([C@H](CC6=CC=C(O)C=C6)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC7=CC=C(O)C=C7)N)=O)CCCCN)=O)C(C)C)=O)CC(N)=O)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)=O)CCC5)[C@@H](C)C)=O)C)=O)CCC4)CO)=O)=O)=O)=O)=O)CC(C)C)=O)=O)CCCNC(=N)N)(=O)N8[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CCCNC(=N)N)=O)CCC8

Molecular Formula

C124H180N34O31

Molecular Weight

2642.97

References & Citations

[1]Liu JJ, et al. Discovery and pharmacological characterization of a small-molecule antagonist at neuromedin U receptor NMUR2. J Pharmacol Exp Ther. 2009 Jul;330 (1) :268-75.