Peptide T (TFA)
Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.
Product Specifications
CAS Number
[1610056-01-3]
UNSPSC
12352209
Target
HIV
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Peptide_T_TFA.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(F)(F)F.OC(C=C1)=CC=C1C[C@@H](C(N[C@H](C(O)=O)[C@H](O)C)=O)NC([C@H](CC(N)=O)NC([C@H](C(O)C)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O
Molecular Formula
C37H56F3N9O18
Molecular Weight
971.89
References & Citations
[1]Ruff MR, et al. Peptide T[4-8] is core HIV envelope sequence required for CD4 receptor attachment. Lancet. 1987 Sep 26;2 (8561) :751.|[2]Ruff MR, et al. Peptide T inhibits HIV-1 infection mediated by the chemokine receptor-5 (CCR5) . Antiviral Res. 2001 Oct;52 (1) :63-75.|[3]Raychaudhuri SP, et al. Immunomodulatory effects of peptide T on Th 1/Th 2 cytokines. Int J Immunopharmacol. 1999 Sep;21 (9) :609-15.|[4]Sáez-Torres I, et al. Peptide T does not ameliorate experimental autoimmune encephalomyelitis (EAE) in Lewis rats. Clin Exp Immunol. 2000 Jul;121 (1) :151-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
HIV-1
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