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Phe-Met-Arg-Phe, amide

Phe-Met-Arg-Phe, amide dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons.

Product Specifications

CAS Number

64190-70-1

UNSPSC

12352209

Target

Potassium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Phe-Met-Arg-Phe,_amide.html

Solubility

10 mM in H2O

Smiles

N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=O)=O

Molecular Formula

C29H42N8O4S

Molecular Weight

598.76

References & Citations

[1]Kits KS, et al. Phe-Met-Arg-Phe-amide activates a novel voltage-dependent K+ current through a lipoxygenasepathway in molluscan neurones. J Gen Physiol. 1997 Nov;110 (5) :611-28.|[2]Sorenson RL, et al. Phe-met-arg-phe-amide (FMRF-NH2) inhibits insulin and somatostatin secretion and anti-FMRF-NH2 sera detects pancreatic polypeptide cells in the rat islet. Peptides. 1984 Jul-Aug;5 (4) :777-82.|[3]Ottlecz A, et al. Phe-Met-Arg-Phe-amide (FMRFamide) stimulated growth hormone secretion in conscious OVX rats. Neuropeptides. 1987 Feb-Mar;9 (2) :161-7.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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