KKI-5

KKI-5 is a specific inhibitor of tissue kallikrein. KKI-5 can attenuate breast cancer cell invasion[1].

Product Specifications

CAS Number

[97145-43-2]

UNSPSC

12352209

Hazard Statement

H302-H315-H319

Target

Kallikrein

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Kallikrein_Inhibitor.html

Solubility

H2O

Smiles

NC(CC[C@@H](C(N)=O)NC([C@H](C(C)C)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CC=CC=C1)NC([C@H]2N(CCC2)C(C)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C35H55N11O9

Molecular Weight

773.88

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35 (17) :3094-102.