Endothelin-2 (49-69), human

Endothelin-2 (49-69), human (Endothelin-2 (human, canine) ) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

Product Specifications

CAS Number

[123562-20-9]

Product Name Alternative

Endothelin-2 (human, canine) ; Human endothelin-2

UNSPSC

12352209

Hazard Statement

H300-H310-H330

Target

Endothelin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Endothelin-2,_human.html

Solubility

H2O

Smiles

O=C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@]1([H])CSSC[C@@](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)C(C)C)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)N)=O)CO)=O)([H])C(N[C@H](C(N[C@H](C(N7)=O)CO)=O)CO)=O)=O)CCC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)CC(C)C)[C@@H]7CC8=CNC9=CC=CC=C89

Molecular Formula

C115H160N26O32S4

Molecular Weight

2546.92

Precautions

P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]Grimshaw MJ, et al. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol. 2002 Sep;32 (9) :2393-400.