Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Deoxynivalenol

Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors[1].

Product Specifications

CAS Number

[51481-10-8]

Product Name Alternative

Vomitoxin

UNSPSC

12352005

Hazard Statement

H300

Target

P-glycoprotein

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/deoxynivalenol.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 30 mg/mL (ultrasonic; warming)

Smiles

O=C(C(C)=C1)[C@@H](O)[C@@]2(CO)[C@]1([H])O[C@]3([H])[C@H](O)C[C@@]2(C)[C@@]34OC4

Molecular Formula

C15H20O6

Molecular Weight

296.32

Precautions

H300

References & Citations

[1]Sergent T, et al. Deoxynivalenol transport across human intestinal Caco-2 cells and its effects on cellularmetabolism at realistic intestinal concentrations. Toxicol Lett. 2006 Jul 1;164 (2) :167-76.|[2]Diesing AK, et al. Mycotoxin deoxynivalenol (DON) mediates biphasic cellular response in intestinal porcine epithelial cell lines IPEC-1 and IPEC-J2. Toxicol Lett. 2011 Jan 15;200 (1-2) :8-18. |[3]Collins TF, et al. Effects of deoxynivalenol (DON, vomitoxin) on in utero development in rats. Food Chem Toxicol. 2006 Jun;44 (6) :747-57.|[4]Pestka JJ, et al. Immunochemical assessment of deoxynivalenol tissue distribution following oral exposure in the mouse. Toxicol Lett. 2008 May 5;178 (2) :83-7.|[5]Forsell JH, et al. Comparison of acute toxicities of deoxynivalenol (vomitoxin) and 15-acetyldeoxynivalenol in the B6C3F1 mouse. Food Chem Toxicol. 1987 Feb;25 (2) :155-62.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N6684/Deoxynivalenol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N6684/Deoxynivalenol-SDS-MedChemExpress.pdf

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Cytokeratin 17 Recombinant Mouse monoclonal Antibody
HA610110 100 µg

Cytokeratin 17 Recombinant Mouse monoclonal Antibody

Ask
View Details
Rabbit anti-Escherichia coli O17:K52:H18 (strain UMN026/ExPEC) MUTL Polyclonal Antibody
MBS7174218 Inquire

Rabbit anti-Escherichia coli O17:K52:H18 (strain UMN026/ExPEC) MUTL Polyclonal Antibody

Ask
View Details
Pigeon Homeobox Protein Hox-D10 (HOXD10) ELISA Kit
MBS9358558 Inquire

Pigeon Homeobox Protein Hox-D10 (HOXD10) ELISA Kit

Ask
View Details
EP300 Recombinant Protein
OPCD02936-10UG 10 µg

EP300 Recombinant Protein

Ask
View Details
Olivil
TN4708 5 mg

Olivil

Ask
View Details
Fmoc-Dab(Boc)-OH
TRC-F628608-1G 1 g

Fmoc-Dab(Boc)-OH

Ask
View Details