Heraclenin
Heraclenin, a natural furanocoumarin, significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT) [1].
Product Specifications
CAS Number
[2880-49-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nuclear Factor of activated T Cells (NFAT)
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/heraclenin.html
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1(C)[C@H](O1)COC2=C(OC=C3)C3=CC(C=C4)=C2OC4=O
Molecular Formula
C16H14O5
Molecular Weight
286.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Márquez N, et al. Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT. Planta Med. 2004 Nov;70 (11) :1016-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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