Uvarigrin
Product Specifications
UNSPSC Description
Uvarigrin, isolated from the roots of Uvaria calamistrata, induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation[1][2].
Target Antigen
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uvarigrin.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CCCCCCCCCCCC[C@H](O)C[C@H]([C@]2([H])O[C@]([C@H](O)CCCCCCCCCCCC)([H])CC2)O)=C[C@H](C)O1
Molecular Weight
608.93
References & Citations
[1]Zhou GX, et al. Calamistrins A and B, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Uvaria calamistrata. J Nat Prod. 1999 Feb;62(2):261-4.|[2]Li YF, et al. Induction of apoptosis of tumor multidrug resistance cell by uvarigrin and its mechanism. Yao Xue Xue Bao. 2006 Mar;41(3):252-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2632/Uvarigrin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2632/
Clinical Information
No Development Reported
CAS Number
200563-11-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
FAB2405D 0.1 mL
Rat Monoclonal Integrin beta 1/CD29 Antibody (265917) [DyLight 350]
Ask
View Details