Evodol

Evodol is a natural product isolated from the dried and nearly ripe fruits of Euodia rutaecarpa. Evodol shows inhibitory activity against NO production[1]. Evodol possesses larvicidal activity against the Asian tiger mosquitoes with a LC50 value of 32.43 μg/ml[2].

Product Specifications

CAS Number

22318-10-1

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/evodol.html

Solubility

10 mM in DMSO

Smiles

C[C@]12[C@@]3([C@@H]4O3)[C@]([C@H](C5=COC=C5)OC4=O)(CC[C@]1([H])[C@]67C(C(C)(C)O[C@@]6([H])CC(OC7)=O)=C(O)C2=O)C

Molecular Formula

C26H28O9

Molecular Weight

484.50

References & Citations

[1]Yang XB, et al. Limonoid constituents of Euodia rutaecarpa var. bodinieri and their inhibition on NO production in lipopolysaccharide-activated RAW264.7 macrophages. J Asian Nat Prod Res. 2013;15 (10) :1130-8.|[2]Liu ZL, et al. Mosquito larvicidal activity of alkaloids and limonoids derived from Evodia rutaecarpa unripe fruits against Aedes albopictus (Diptera: Culicidae) .Parasitol Res. 2012 Sep;111 (3) :991-6.