IKarisoside A

IKarisoside A (Icarisoside-A) is a natural flavonol glycoside and has anti-inflammatory properties.

Product Specifications

CAS Number

[55395-07-8]

Product Name Alternative

Icarisoside-A; Baohuoside II

UNSPSC

12352005

Hazard Statement

H315, H319

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/IKarisoside-A.html

Purity

99.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC(O)=C2C(OC(C3=CC=C(O)C=C3)=C(O[C@H](O[C@@H](C)[C@H](O)[C@H]4O)[C@@H]4O)C2=O)=C1C/C=C(C)\C

Molecular Formula

C26H28O10

Molecular Weight

500.49

Precautions

H315, H319

References & Citations

[1]Choi HJ, et al. Ikarisoside A inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated RAW 264.7 cells via p38 kinase and nuclear factor-kappaB signaling pathways. Eur J Pharmacol. 2008 Dec 28;601 (1-3) :171-8.|[2]Choi HJ, eta l. Inhibition of osteoclastogenic differentiation by Ikarisoside A in RAW 264.7 cells via JNK and NF-kappaB signaling pathways. Eur J Pharmacol. 2010 Jun 25;636 (1-3) :28-35.|[3]Li X, Toyohira Y, Horisita T, et al. Ikarisoside A inhibits acetylcholine-induced catecholamine secretion and synthesis by suppressing nicotinic acetylcholine receptor-ion channels in cultured bovine adrenal medullary cells. Naunyn Schmiedebergs Arch Pharmacol. 2015;388 (12) :1259-1269.