Phytic acid (dodecasodium hydrate)

Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4].

Product Specifications

CAS Number

[123408-98-0]

Product Name Alternative

Inositol hexaphosphate (dodecasodium hydrate) ; SNF472 (dodecasodium hydrate)

UNSPSC

12352128

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Xanthine Oxidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/phytic-acid-dodecasodium-hydrate.html

Purity

98.0

Solubility

10 mM in DMSO|H2O : ≥ 250 mg/mL

Smiles

O=P(O[Na])(O[Na])O[C@H]1[C@H]([C@H]([C@H](OP(O[Na])(O[Na])=O)[C@@H](OP(O[Na])(O[Na])=O)[C@@H]1OP(O[Na])(O[Na])=O)OP(O[Na])(O[Na])=O)OP(O[Na])(O[Na])=O.[x].O

Molecular Formula

C6H6O24P6.xH2O.12Na

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhou JR, et al. Phytic acid in health and disease. Crit Rev Food Sci Nutr. 1995 Nov;35 (6) :495-508.|[2]Gupta RK, et al. Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains. J Food Sci Technol. 2015 Feb;52 (2) :676-84.|[3]Muraoka S, et al. Inhibition of xanthine oxidase by phytic acid and its antioxidative action. Life Sci. 2004 Feb 13;74 (13) :1691-700.|[4]Lv Y, et al. Phytic acid attenuates inflammatory responses and the levels of NF-κB and p-ERK in MPTP-induced Parkinson's disease model of mice. Neurosci Lett. 2015 Jun 15;597:132-6.