Phellodendrine
Product Specifications
UNSPSC Description
Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendron amurense. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect [1].
Target Antigen
Akt; NF-κB
Type
Natural Products
Related Pathways
NF-κB;PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/phellodendrine.html
Purity
99.60
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
OC1=C(OC)C=C2CC[N@@+]3(C)CC4=CC(OC)=C(O)C=C4C[C@@]3([H])C2=C1
Molecular Weight
342.41
References & Citations
[1]Li L , et al. The defensive effect of phellodendrine against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway in zebrafish embryos. Life Sci. 2016 Jul 15;157:97-106.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0427/Phellodendrine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0427/Phellodendrine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
6873-13-8
Curated Selection
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