Chavicol
Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase (Cholinesterase (ChE) ), with an IC50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells[1][2].
Product Specifications
CAS Number
501-92-8
Product Name Alternative
P-Hydroxyallylbenzene
UNSPSC
12352005
Hazard Statement
H316, H319, H335
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/chavicol.html
Purity
97.99
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
C=CCC1=CC=C(C=C1)O
Molecular Formula
C9H10O
Molecular Weight
134.18
Precautions
H316, H319, H335
References & Citations
[1]Haixiao Lu, et al. Tzumin A and B, two new lignan derivatives from the barks of Sassafras tzumu. Nat Prod Res. 2017 Apr;31 (7) :829-834.|[2]Chellasamy Panneerselvam, et al. Anticancer activity of bioactive compound chavicol as potential toxic against human lung cancer A549 cells. Journal of Drug Delivery Science and Technology. Volume 73, July 2022, 103442.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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