Chavicol

Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase (Cholinesterase (ChE) ), with an IC50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells[1][2].

Product Specifications

CAS Number

[501-92-8]

Product Name Alternative

P-Hydroxyallylbenzene

UNSPSC

12352005

Hazard Statement

H316, H319, H335

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/chavicol.html

Purity

97.99

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

C=CCC1=CC=C(C=C1)O

Molecular Formula

C9H10O

Molecular Weight

134.18

Precautions

H316, H319, H335

References & Citations

[1]Haixiao Lu, et al. Tzumin A and B, two new lignan derivatives from the barks of Sassafras tzumu. Nat Prod Res. 2017 Apr;31 (7) :829-834.|[2]Chellasamy Panneerselvam, et al. Anticancer activity of bioactive compound chavicol as potential toxic against human lung cancer A549 cells. Journal of Drug Delivery Science and Technology. Volume 73, July 2022, 103442.