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Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1)

Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) is a rat-derived IgG2b κ type antibody inhibito, targeting to mouse CD122/IL-2Rβ. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can block IL-2 and IL-15. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can deplete natural killer (NK) cells and NKT cells. Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) can be used for the researches of cancer, infection, inflammation, immunology and metabolic disease, such as melanoma, experimental autoimmune encephalomyelitis (EAE) and diabetes[1][2][3][4].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd122-il-2rβ-antibody-tm-beta-1.html

Purity

95

Smiles

[Anti-MouseCD122/IL-2RbAntibody(TM-Beta1)]

Molecular Weight

(150 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Yu P, et al. IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells. Eur J Immunol. 2014 Nov;44 (11) :3330-41.|[2]Brauner H, et al. Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice. Immunol Cell Biol. 2016 Feb;94 (2) :177-84.|[3]Nishikawa Y, et al. Roles of CD122+ cells in resistance against Neospora caninum infection in a murine model. J Vet Med Sci. 2010 Oct;72 (10) :1275-82.|[4]Lacher SB, et al. PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells. Nature. 2024 May;629 (8011) :417-425.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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