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Carbenicillin

Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue[1][2].

Product Specifications

CAS Number

4697-36-3

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/carbenicillin.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(C(O)=O)C3=CC=CC=C3)=O)N1C2=O)O

Molecular Formula

C17H18N2O6S

Molecular Weight

378.40

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Scott RE, et, al. Synergistic activity of carbenicillin and gentamicin in experimental Pseudomonas bacteremia in neutropenic rats. Antimicrob Agents Chemother. 1976 Oct;10 (4) :646-51. |[2]Neu HC, et, al. Carbenicillin and ticarcillin. Med Clin North Am. 1982 Jan;66 (1) :61-77.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Citation 01

Antimicrob Agents Chemother. 2023 Jun 15;67 (6) :e0160322.|Microbiol Spectr. 2023 Feb 14;11 (1) :e0303822.|Microbiol Spectr. 2023 Jun 15;11 (3) :e0069223.|ChemRxiv. 2020 Apr.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|Molecules. 2025 Mar 9;30 (6) :1224.

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