Azaphen

Pipofezine (Azafen, Azaphen) is a serotonin reuptake inhibitor.

Product Specifications

CAS Number

[24853-80-3]

Product Name Alternative

Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride

UNSPSC

12352005

Target

Serotonin Transporter

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/azaphen.html

Solubility

10 mM in DMSO

Smiles

[H]Cl.[H]Cl.CN1C2=CC=CC=C2OC3=C1C=C(N4CCN(C)CC4)N=N3

Molecular Formula

C16H21Cl2N5O

Molecular Weight

370.28

References & Citations

[1]Domestic antidepressants. 1. Azaphen By Andreeva, N. I.; Asnina, V. V.; Liberman, S. S. From Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34 (5), 237-241.|[2]Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105 (10) :55-6.|[3]Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11 (1) :29-33.|[4]Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38 (1) :29-32.|[5]Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha) . 1974;16 (4) :245-6.