ATB107
ATB107 is a potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.
Product Specifications
CAS Number
455325-51-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ATB107.html
Purity
99.36
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C1(N2CCCCC2)=NC(NC3=CC=CC=C3)=NC(N/N=C4CN5CCC\4CC5)=N1
Molecular Formula
C21H28N8
Molecular Weight
392.50
References & Citations
[1]Shen H, et al. A novel inhibitor of indole-3-glycerol phosphate synthase with activity against multidrug-resistant Mycobacterium tuberculosis. FEBS J. 2009 Jan;276 (1) :144-54.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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