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ATB107

ATB107 is a potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.

Product Specifications

CAS Number

[455325-51-6]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ATB107.html

Purity

99.36

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C1(N2CCCCC2)=NC(NC3=CC=CC=C3)=NC(N/N=C4CN5CCC\4CC5)=N1

Molecular Formula

C21H28N8

Molecular Weight

392.50

References & Citations

[1]Shen H, et al. A novel inhibitor of indole-3-glycerol phosphate synthase with activity against multidrug-resistant Mycobacterium tuberculosis. FEBS J. 2009 Jan;276 (1) :144-54.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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