MCAK Recombinant Rabbit Monoclonal Antibody [PSH01-51]

This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

4930402F02Rik antibody CT139 antibody ESTM5 antibody KIF 2C antibody kif2c antibody KIF2C_HUMAN antibody Kinesein Family Member 2C antibody Kinesin family member 2C antibody kinesin like 6 (mitotic centromere associated kinesin) antibody Kinesin like 6 antibody Kinesin like protein 6 antibody Kinesin like protein KIF2C antibody Kinesin-like protein 6 antibody Kinesin-like protein KIF2C antibody KNS L6 antibody KNSL 6 antibody KNSL6 antibody MCAK antibody MGC11883 antibody Mitotic centromere associated kinesin antibody Mitotic centromere-associated kinesin antibody OTTHUMP00000010066 antibody X83316 antibody

Abbreviation

Kinesin-like protein KIF2C Kinesin-like protein 6 Mitotic centromere-associated kinesin (MCAK) KIF2C KNSL6

Swiss Prot

Q99661 Human

Cellular Locus

Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human MCAK aa 200-650.

Isotype

IgG

Clone

PSH01-51

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

HeLa cell lysate, HepG2 cell lysate, K-562 cell lysate, Jurkat cell lysate, 293T cell lysate, human testis tissue, mouse testis tissue, rat testis tissue.