Cinepazide

Cinepazide is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain infarct et. al[1].

Product Specifications

CAS Number

[23887-46-9]

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cinepazide.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(CC(N2CCCC2)=O)CC1)/C=C/C3=CC(OC)=C(OC)C(OC)=C3

Molecular Formula

C22H31N3O5

Molecular Weight

417.50

References & Citations

[1]Akashi, A., et al., [Cardiovascular pharmacology of cinepazide, a new cerebral vasodilator (author's transl) ]. Nihon Yakurigaku Zasshi, 1979. 75 (5) : p. 507-16.|[2]Jonathan G Swoboda, et al. Small molecule mediated proliferation of primary retinal pigment epithelial cells. ACS Chem Biol. 2013 Jul 19;8 (7) :1407-11.