Clemizole
Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole is an inhibitor of TRPC5 channel. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 μM.
Product Specifications
CAS Number
442-52-4
UNSPSC
12352005
Target
HCV; HCV Protease; Histamine Receptor; TRP Channel
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Clemizole.html
Concentration
10mM
Purity
98.42
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(C=C1)CN2C(CN3CCCC3)=NC4=CC=CC=C24
Molecular Formula
C19H20ClN3
Molecular Weight
325.84
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
SARS-CoV-2 RBD Domain produced in Yeast, C-His Tag
SARS-CoV-2 RBD Domain produced in Yeast, C-His Tag
