DTAG Targeting Ligand 1
DTAG Targeting Ligand 1 (SUBSTITUTE SHEET 245) is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC) . dTAG Targeting Ligand 1 can be used for synthesis PROTACs[1].
Product Specifications
CAS Number
[755039-56-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for Target Protein for PROTAC; Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dtag-targeting-ligand-1.html
Purity
98.0
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1[C@@H](CC)N(C2CCCC2)C3=NC(NC4=C(OC)C=C(C=C4)C(O)=O)=NC=C3N1C
Molecular Formula
C22H27N5O4
Molecular Weight
425.48
Precautions
H302, H315, H319, H335
References & Citations
[1]J. Bradner, et al. Targeting proteins are degraded to weaken the relevant bad inflammatory reaction of adoptive T cell therapy. CN108350062A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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