Inogatran
Inogatran (H-314-27) is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases.
Product Specifications
CAS Number
155415-08-0
Product Name Alternative
H-314-27
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Inogatran.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CN[C@H](CC1CCCCC1)C(N2[C@H](C(NCCCNC(N)=N)=O)CCCC2)=O
Molecular Formula
C21H38N6O4
Molecular Weight
438.56
References & Citations
[1]Ignasiak DP, et al. Effects of Intravenous Enoxaparin and Intravenous Inogatran in an Electrolytic Injury Model of Venous Thrombosis in the Dog. J Thromb Thrombolysis. 1998 Nov;6 (3) :199-206.|[2]Chi L, et al. Antithrombotic effect of LB-30057 (CI-1028), a new synthetic thrombin inhibitor, in a rabbit model of thrombosis: comparison with inogatran. J Thromb Thrombolysis. 2001 Feb;11 (1) :19-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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