(-) -GSK598809
(-) -GSK598809 ((1S,5R) -GSK598809) is an isomer of GSK598809. GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist.
Product Specifications
CAS Number
[863680-46-0]
Product Name Alternative
(1S,5R) -GSK598809
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1s-5r-gsk598809.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=NN=C(SCCCN3C[C@@]4(C5=CC=C(C(F)(F)F)C=C5F)C[C@@]4([H])C3)N2C)OC=N1
Molecular Formula
C22H23F4N5OS
Molecular Weight
481.51
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Appel NM, et al. Dopamine D3 Receptor Antagonist (GSK598809) Potentiates the Hypertensive Effects of Cocaine in Conscious, Freely-Moving Dogs. J Pharmacol Exp Ther. 2015 Sep;354 (3) :484-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D3 Receptor
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
BPE035-01 96 Tests
Human Neuroblastoma Suppressor Of Tumorigenicity 1, NBL1 Primacu™ ELISA Kit
Ask
View Details BPE035-02 5x 96 Tests
Human Neuroblastoma Suppressor Of Tumorigenicity 1, NBL1 Primacu™ ELISA Kit
Ask
View Details