UK-240455
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist.
Product Specifications
CAS Number
178908-09-3
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/UK-240455.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(N(C1=C(Cl)C(Cl)=CC(NC2=O)=C1NC2=O)CCO)=O
Molecular Formula
C11H11Cl2N3O5S
Molecular Weight
368.19
References & Citations
[1]Webster R, et al. Pharmacokinetics and disposition of a novel NMDA glycine site antagonist (UK-240,455) in rats, dogs and man. Xenobiotica. 2003 May;33 (5) :541-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
NMDA Receptor
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