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Rimeporide hydrochloride

Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1) .

Product Specifications

CAS Number

187870-95-7

Product Name Alternative

EMD-87580 hydrochloride

UNSPSC

12352005

Target

Na+/H+ Exchanger (NHE)

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Rimeporide_(hydrochloride).html

Solubility

10 mM in DMSO

Smiles

O=C(NC(N)=N)C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C.Cl

Molecular Formula

C11H16ClN3O5S2

Molecular Weight

369.84

References & Citations

[1]F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Frequently Asked Questions

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