L-159282

L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity.

Angiotensin Receptor

Reference compound

GPCR/G Protein

Metabolism-protein/nucleotide metabolism

Cardiovascular Disease; Endocrinology

https://www.medchemexpress.com/L-159282.html

10 mM in DMSO

O=C(NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CC)=NC4=C(C)C=C(C)N=C43)C=C2)=O)C5=CC=CC=C5

524.63

[1]Kivlighn SD, et al. In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996. Am J Hypertens. 1995 Jan;8(1):58-66.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-19191/L-159282-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-19191/

Phase 2

157263-00-8