L-159282
L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity.
Product Specifications
CAS Number
[157263-00-8]
Product Name Alternative
MK 996
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/L-159282.html
Solubility
10 mM in DMSO
Smiles
O=C(NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CC)=NC4=C(C)C=C(C)N=C43)C=C2)=O)C5=CC=CC=C5
Molecular Formula
C30H28N4O3S
Molecular Weight
524.63
References & Citations
[1]Kivlighn SD, et al. In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996. Am J Hypertens. 1995 Jan;8 (1) :58-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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