RG-12915
RG-12915 is a selective 5-HT3 antagonist, with IC50 value of 0.16 nM.
Product Specifications
CAS Number
136174-04-4
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RG-12915.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C2O[C@](CCCC3)([H])[C@]3([H])C2=CC(Cl)=C1)N[C@@H]4CN5CCC4CC5
Molecular Formula
C20H25ClN2O2
Molecular Weight
360.88
References & Citations
[1]Fitzpatrick LR, et al. RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog. J Pharmacol Exp Ther. 1990 Aug;254 (2) :450-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
Lactoferrin
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7165608 Inquire
Rabbit anti-Escherichia coli O6:H1 (strain CFT073/700928/UPEC) YAIA Polyclonal Antibody
Sign In for Pricing
View Details 
JOT-AP04530-01 20 µL
ROS(Phospho Tyr2114) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details JOT-AP04530-02 50 μL
ROS(Phospho Tyr2114) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details JOT-AP04530-03 100 µL
ROS(Phospho Tyr2114) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details K4542007 1.0 µg DNA
Rdm1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details