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SM-6586

SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.

Product Specifications

CAS Number

[103898-38-0]

UNSPSC

12352005

Target

Calcium Channel; Na+/Ca2+ Exchanger

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/SM-6586.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C)NC(C)=C(C2=NC(CN(C)CC3=CC=CC=C3)=NO2)C1C4=CC=CC([N+]([O-])=O)=C4)OC

Molecular Formula

C26H27N5O5

Molecular Weight

489.52

References & Citations

[1]Kashiwagi F, et al. Effect of a new calcium antagonist (SM-6586) on experimental cerebral ischemia. Acta Neurochir Suppl (Wien) . 1994;60:289-92.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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