SM-6586
SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.
Product Specifications
CAS Number
103898-38-0
UNSPSC
12352005
Target
Calcium Channel; Na+/Ca2+ Exchanger
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/SM-6586.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)NC(C)=C(C2=NC(CN(C)CC3=CC=CC=C3)=NO2)C1C4=CC=CC([N+]([O-])=O)=C4)OC
Molecular Formula
C26H27N5O5
Molecular Weight
489.52
References & Citations
[1]Kashiwagi F, et al. Effect of a new calcium antagonist (SM-6586) on experimental cerebral ischemia. Acta Neurochir Suppl (Wien) . 1994;60:289-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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