Arg-Gly-Asp (TFA)
Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1. It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.
Product Specifications
CAS Number
[120103-89-1]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arg-gly-asp-tfa.html
Smiles
O=C(O)C[C@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)N)=O)=O.O=C(O)C(F)(F)F
Molecular Formula
C14H23F3N6O8
Molecular Weight
460.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ruoslahti, et al. RGD and other recognition sequences for integrins. Annu. Rev. Cell Dev. Biol. 12, 697-715 (1996) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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