Micafungin
Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.
Product Specifications
CAS Number
235114-32-6
Product Name Alternative
FK463
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/micafungin.html
Purity
98.91
Solubility
10 mM in DMSO
Smiles
O=C([C@](NC(C(NC([C@@](C[C@@H](O)C1)([H])N1C2=O)=O)[C@H](O)[C@H](C3=CC(OS(=O)(O)=O)=C(O)C=C3)O)=O)([H])[C@H](O)CC(N)=O)N4[C@@](C(N[C@@H]([C@@H](C[C@@H](C(NC2[C@H](O)C)=O)NC(C5=CC=C(C6=NOC(C7=CC=C(OCCCCC)C=C7)=C6)C=C5)=O)O)O)=O)([H])[C@@H](O)[C@@H](C)C4
Molecular Formula
C56H71N9O23S
Molecular Weight
1270.27
Precautions
H302, H312, H332
References & Citations
[1]Micafungin, From Wikipedia
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
BioRxiv. 2025 Feb 6:2025.02.05.636768.|Infect Drug Resist. 2022 Dec 15:15:7459-7473.|J Antimicrob Chemother. 2020 Aug 1;75 (8) :2133-2140.|J Microbiol Methods. 2021 Nov:190:106327.|Microorganisms. 2022 Dec 21;11 (1) :23.|Microorganisms. 2023 Jun 18;11 (6) :1608.|mSphere. 2018 Nov 14;3 (6) . pii: e00547-18.|mSphere. 2020 Oct 28;5 (5) :e00821-20.|Mycoses. 2021 Mar;64 (3) :282-291.|Antimicrob Agents Chemother. 2023 Aug 17;67 (8) :e0054323.|Appl Microbiol Biotechnol. 2025 Jan 24;109 (1) :21.|bioRxiv. 2024 May 14.|Chem Biol Interact. 2024 Jul 31:400:111179.|J Clin Microbiol. 2017 Jun;55 (6) :1883-1893.|NPJ Antimicrob Resist. 2025 Apr 17;3 (1) :31.|PLoS Negl Trop Dis. 2019 Aug 20;13 (8) :e0007681. |Sci Rep. 2017 Feb 17;7:42886.
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